Nanobody/VHH Discovery Service
Nanobody is the variable domain of heavy chain-only antibody (HcAb) first isolated from the serum of Camelidae family about 20 years ago. Nanobody is 4 nm in length, 2.5 nm in width. It has a molecular weight of 15 kD, only 1/10 the size of conventional monoclonal antibodies (mAbs) attributed to lacking the light chain (L) and heavy chain constant domains (CH). Nanobody exhibits high specificity and affinity and outperforms conventional antibody in many aspects, such as high stability, great water-solubility and easy and feasible development process.
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